Enabling Deep Brain Imaging In-Vivo for Neuroscience Applications

DeepEn One is an ultra-minimally invasive holographic microendoscope that enables high-resolution imaging deep inside the brain. Using holographic light control through a single 100 µm multimode fibre, it delivers sub-cellular detail without the need for bulky lenses or extensive surgery. The system includes a compact benchtop unit, intuitive software, and single-use fibre probes. It allows neuroscientists to visualise structure and activity in previously inaccessible brain regions—advancing research on learning, memory, and disease.